We do research to learn more about our speciality. We then publish this to share what we have learned, so that others can benefit too. Research and experience benefit no one unless they are freely available to others.
Here is sample of our recent publications in Immunology and Allergy. You can find out more by searching the web using the “DOI” number on the end of each article. You can also contact the department for more information.
Aygören-Pürsün E, et al (2018) Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema. New England Journal of Medicine 379 (4), 352-362
Cuchet-Louren D, et al.,(2018) Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation. Science 361(6404):810-813. DOI: 10.1126/science.aar2641
M Zaman, A Huissoon, M Buckland et al. (2018) Clinical & laboratory features of seventy‐eight UK patients with Good’s syndrome (thymoma & hypogammaglobulinemia) Clin Exp Immunology (in press). doi: 10.1111/cei.13216.
Mohamed O, et al. A (2018) Retrospective Critical Analysis and Risk Stratification of Penicillin Allergy Delabeling in a UK Specialist Regional Allergy Service. Journal of Allergy and Clinical Immunology: In Practice, (in press). doi.org/10.1016/j.jaip.2018.05.025.
Shillitoe B, et al. (2018). The United Kingdom Primary Immune Deficiency (UKPID) Registry 2012 to 2017 Clin Exp Immunology;192(3):284-291 doi.org/10.1111/cei.13125
Beck SC, Huissoon AP, Collins D, Richter AG, Krishna MT (2018). The concordance between component tests and clinical history in British adults with suspected pollen-food syndrome (PFS) to peanut and hazelnut. Journal of Clinical Pathology 71: 239-245.
Evans C et al. (2018) Measurement of Typhim Vi antibodies can be used to assess adaptive immunity in patients with immunodeficiency. Clin Exp Immunology: 192(3):292-301. (doi.org/10.1111/cei.13105)
Staples E, et al. Disseminated Mycobacterium malmoense and Salmonella Infections Associated with a Novel Variant in NFKBIA. J Clin Immunol. 2017 Jul;37(5):415-418
Rajakulasingam RK, Farah N, Huber PAJ, Durham SR, Clark AT, Nasser SM, Krishna MT (2017). Practice and safety of allergen-specific immunotherapy for allergic rhinitis in the UK national health service: A report of “real world” clinical practice. Clin Exp Allergy. 2018 Jan;48(1):89-92. doi: 10.1111/cea.13052.
Battersby AC, et al.(2017) Inflammatory and autoimmune manifestations in X-linked carriers of chronic granulomatous disease in the United Kingdom. J Allergy Clin Immunol. 140(2):628-630.e6. doi: 10.1016/j.jaci.2017.02.029
Hurst JR, et al. (2017). BLF/UKPIN Consensus Statement on the Definition, Diagnosis and Management of Granulomatous-Lymphocytic Interstitial Lung Disease (GLILD) in Common Variable Immunodeficiency Disorders (CVID). JACI: In Practice. 5(4): 938 – 94.
Battersby AC, et al. (2017) Inflammatory and autoimmune manifestations in X-linked carriers of chronic granulomatous disease in the United Kingdom. J Allergy Clin Immunol. 140(2):628-630 doi: 10.1016/j.jaci.2017.02.029
Krishna MT, et al. (2017) Enhancing antibiotic stewardship by tackling ‘spurious’ penicillin allergy. Clinical & Experimental Allergy;47(11):1362–73
Record J et al. (2015) Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1. Blood. 2015 Sep 24;126(13):1527-35
Baretto RL, et al. (2017).Validation of International consensus equation for acute serum total tryptase in mast cell activation: A perioperative perspective. Allergy;72(12):2031–4 (DOI: 10.1111/all.13226)
Wong GK, et al. (2016). Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency. Journal of Immunol 197:1642-1649, doi:10.4049/jimmunol.1600526
Krishna MT, Huissoon AP. Peri-operative anaphylaxis – beyond drugs and latex. Int Arch Allergy Immunol 2015;167(2):101-2. DOI:10.1159/000436971.
Buka RJ, et al (2015). Anaphylaxis and ethnicity: higher incidence in British South Asians. Allergy;70(12):1580–1587. DOI: 10.1111/all.12702
Record J, et al (2015). Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1. Blood. pii: blood-2014-12-611012
Bahal S, et al (2015). Absent AB isoagglutinins: a clue to immunodeficiency. Transfusion Medicine; 25(3):201-3. doi: 10.1111/tme.12213.
Turley AJ, et al (2015) Spectrum and Management of Complement Immunodeficiencies (Excluding Hereditary Angioedema) Across Europe. J Clin Immunol 35(2):199-205. DOI 10.1007/s10875-015-0137-5.
Krishna MT, et al (2015). Multi-centre retrospective analysis of anaphylaxis during general anaesthesia in the United Kingdom: aetiology and diagnostic performance of acute serum tryptase. Clinical & Experimental Immunology;178(2):399-404
Srivastava S, et al (2014). Systemic reactions and anaphylaxis with an acute serum tryptase ≥14 μg/L: retrospective characterisation of aetiology, severity and adherence to National Institute of Health and Care Excellence (NICE) guidelines for serial tryptase measurements and specialist referral. Journal of Clinical Pathology 67(7):614-9
Adalat S et al. (2014) Toxic shock syndrome surveillance in UK children. Arch Dis Child; 99(12):1078-82. doi: 10.1136/archdischild-2013-304741
Edgar et al (2014). The United Kingdom Primary Immune Deficiency (UKPID) Registry: Report of the first 4 years’ activity 2008-2012. Clinical & Experimental Immunology; 175(1): 68–78.
Jolles S, et al (2014). A UK National Audit of Hereditary and Acquired Angioedema. Clinical and Experimental Immunology Clinical & Experimental Immunology; 175(1):59–67
Wong G, et al (2013). Outcomes of splenectomy in patients with common variable immunodeficiency (CVID): a survey of 45 patients. Clinical & Experimental Immunology; 172(1):1365-2249.
Dretzke J, et al (2013). Subcutaneous and sublingual immunotherapy for seasonal allergic rhinitis: A systematic review and indirect comparison. Journal of Allergy and Clinical Immunology;131(5):1361-1366
Meadows A, et al (2013). A systematic review and economic evaluation of sublingual and subcutaneous allergen immunotherapy in adults and children with severe hay fever. Health Technology Assessment; 17(27)
Jyothi S et al. (2013) Immune deficiencies in children: an overview. Postgrad Med J.; 89(1058):698-708. doi: 10.1136/postgradmedj-2012-302278rep
Hambleton S et al. (2013) STAT2 deficiency and susceptibility to viral illness in humans. Proc Natl Acad Sci U S A.; 110(8):3053-8. doi: 10.1073/pnas.1220098110