We do research to learn more about our speciality. We then publish this to share what we have learned, so that others can benefit too. Research and experience benefit no one unless they are freely available to others.

Complement paperPenicillin allergy

Here is sample of our recent publications in Immunology and Allergy. You can find out more by searching the web using the “DOI” number on the end of each article. You can also contact the department for more information.

Aygören-Pürsün E, et al. (2018) Prevention of Hereditary Angioedema Attacks with BCX7353, an Oral Plasma Kallikrein Inhibitor. (In press)

Shillitoe B, et al. (2018). The United Kingdom Primary Immune Deficiency (UKPID) Registry 2012 to 2017 Clin Exp Immunology;192(3):284-291 doi.org/10.1111/cei.13125

Beck SC, Huissoon AP, Collins D, Richter AG, Krishna MT (2018). The concordance between component tests and clinical history in British adults with suspected pollen-food syndrome (PFS) to peanut and hazelnut. Journal of Clinical Pathology 71: 239-245.

Evans C et al. (2018) Measurement of Typhim Vi antibodies can be used to assess adaptive immunity in patients with immunodeficiency. Clinical and Experimental Immunology: 192(3):292-301.(doi.org/10.1111/cei.13105)

Hurst JR, et al. (2017). BLF/UKPIN Consensus Statement on the Definition, Diagnosis and Management of Granulomatous-Lymphocytic Interstitial Lung Disease (GLILD) in Common Variable Immunodeficiency Disorders (CVID).  JACI: In Practice.  5(4): 938 – 94.

Battersby AC, et al. (2017) Inflammatory and autoimmune manifestations in X-linked carriers of chronic granulomatous disease in the United Kingdom.. J Allergy Clin Immunol. 140(2):628-630 doi: 10.1016/j.jaci.2017.02.029

Krishna MT, et al. (2017) Enhancing antibiotic stewardship by tackling ‘spurious’ penicillin allergy. Clinical & Experimental Allergy;47(11):1362–73

Baretto RL, et al. (2017).Validation of International consensus equation for acute serum total tryptase in mast cell activation: A perioperative perspective. Allergy;72(12):2031–4 (DOI: 10.1111/all.13226)

Wong GK, et al. (2016). Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency. Journal of Immunol 197:1642-1649, doi:10.4049/jimmunol.1600526

Krishna MT, Huissoon AP. Peri-operative anaphylaxis – beyond drugs and latex. Int Arch Allergy Immunol 2015;167(2):101-2. DOI:10.1159/000436971.

Buka PaperBuka RJ, et al (2015). Anaphylaxis and ethnicity: higher incidence in British South Asians. Allergy;70(12):1580–1587.  DOI: 10.1111/all.12702

Record J, et al (2015). Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1. Blood. pii: blood-2014-12-611012

Bahal S, et al (2015). Absent AB isoagglutinins: a clue to immunodeficiency. Transfusion Medicine; 25(3):201-3.  doi: 10.1111/tme.12213.

Turley AJ, et al (2015) Spectrum and Management of Complement Immunodeficiencies (Excluding Hereditary Angioedema) Across Europe. J Clin Immunol 35(2):199-205. DOI 10.1007/s10875-015-0137-5.

Krishna MT, et al  (2015). Multi-centre retrospective analysis of anaphylaxis during general anaesthesia in the United Kingdom: aetiology and diagnostic performance of acute serum tryptase. Clinical &  Experimental Immunology;178(2):399-404

Lu W et al. (2014) Dual proteolytic pathways govern glycolysis and immune competence. Cell;159(7):1578-90. doi: 10.1016/j.cell.2014.12.001.Bahal isoagglutinins

Srivastava S, et al (2014). Systemic reactions and anaphylaxis with an acute serum tryptase ≥14 μg/L: retrospective characterisation of aetiology, severity and adherence to National Institute of Health and Care Excellence (NICE) guidelines for serial tryptase measurements and specialist referral. Journal of Clinical Pathology 67(7):614-9

Adalat S et al. (2014) Toxic shock syndrome surveillance in UK children. Arch Dis Child; 99(12):1078-82. doi: 10.1136/archdischild-2013-304741

Edgar et al (2014). The United Kingdom Primary Immune Deficiency (UKPID) Registry: Report of the first 4 years’ activity 2008-2012. Clinical & Experimental Immunology; 175(1): 68–78.

Jolles S, et al (2014).  A UK National Audit of Hereditary and Acquired Angioedema. Clinical and Experimental Immunology Clinical & Experimental Immunology; 175(1):59–67

Wong G, et al (2013). Outcomes of splenectomy in patients with common variable immunodeficiency (CVID): a survey of 45 patients. Clinical & Experimental Immunology; 172(1):1365-2249.

SCIT-SLIT systematic reviewDretzke J, et al (2013). Subcutaneous and sublingual immunotherapy for seasonal allergic rhinitis: A systematic review and indirect comparison. Journal of Allergy and Clinical Immunology;131(5):1361-1366

Meadows A, et al (2013). A systematic review and economic evaluation of sublingual and subcutaneous allergen immunotherapy in adults and children with severe hay fever. Health Technology Assessment; 17(27)

Jyothi S et al. (2013) Immune deficiencies in children: an overview. Postgrad Med J.; 89(1058):698-708. doi: 10.1136/postgradmedj-2012-302278rep

Hambleton S et al. (2013) STAT2 deficiency and susceptibility to viral illness in humans. Proc Natl Acad Sci U S A.; 110(8):3053-8. doi: 10.1073/pnas.1220098110