Immunodeficiency disorders are rare. High quality clinical research often requires large numbers of patients, so Immunology Centres in the UK and internationally collaborate to increase the numbers of patients studied. This is the only way that we can learn more about these rare conditions and develop new treatments.

Listed here are some of the trials and studies undertaken at the West Midlands Immunodeficiency Centre. If you are interested in participating in a trial, contact the investigator listed,


Trial Description Investigator Status
UKPIN / ESID database This UK and European study collects anonymous information about patients with any immunodeficiency disorder. Our aim is to contribute data from all of our patients, with their consent


Dr Aarn Huissoon Open
STILPAD study Observational study of interstitial lung disease in CVID


Dr Aarn Huissoon Closed
IOS Survey of treatment of HAE attacks Dr Anjali Ekbote Open

Saftey study of new oral treatment to prevent HAE.


Dr Aarn Huissoon Open
APeX-1 New oral treatment to prevent attacks of HAE Dr Aarn Huissoon Closed

Genomic studies in immunodeficiency


Dr Aarn Huissoon Closed
Genomics England 100K Genome project Whole genome testing in immunodeficiency


Dr Aarn Huissoon Closed
XLA Quality of Life  Questionnaire-based study to examine quality of life in patients with XLA immunodeficiency Dr Scott Hackett Open
Causes of CVID  

Laboratory investigations to investigate the factors that may lead to CVID


Dr Aarn Huissoon Open
OPuS-2 New oral treatment to prevent attacks of hereditary angioedema (HAE) Dr Aarn Huissoon Closed



Still under construction!